Information about Papaverine
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Papaverine
Precautions:
Heart: Large doses can produce serious arrhythmias (irregular heartbeats). Liver sensitivity has been reported with intestinal symptoms, yellowing of the skin and eyes and altered liver function tests. Discontinue medication if these symptoms occur.
Pregnancy: Adequate studies have not been done in pregnant women or animal studies may have shown a risk to the fetus. Use only if clearly needed and potential benefits outweigh the possible hazards to the fetus.
Breastfeeding: It is not known if papaverine appears in breast milk. Consult your doctor before you begin breastfeeding.
Children: Safety and effectiveness have not been established.
Drug Interactions:
Tell your doctor or pharmacist if you are taking or planning to take any overthe-counter or prescription medications or dietary supplements with papaverine. Doses of one or both drugs may need to be modified or a different drug may need to be prescribed. Levodopa (eg, Larodopa) interacts with papaverine.
Side Effects of The Papaverine:
Every drug is capable of producing side effects. Many papaverine users experience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dosage, duration of therapy, and individual susceptibility. Possible side effects include:
Digestive Tract: Nausea; stomachache; appetite loss; constipation; diarrhea.
Nervous System: Headache; dizziness; drowsiness; feeling of whirling motion.
Circulatory System: Increased heart rate; increased blood pressure. Skin: Yellowing of skin or eyes; sweating; flushing of face; rash.
Other: Fatigue and general body aches; increase in depth of respirations; abnormal liver tests.
Guidelines for Use:
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May cause drowsiness or dizziness. Use caution when driving or performing tasks requiring alertness. Alcohol may intensify these effects.
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May cause flushing, sweating, headache, tiredness, jaundice, rash, nausea, appetite loss, abdominal distress, constipation or diarrhea. Notify your doctor if these effects become pronounced.
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Take at evenly spaced intervals throughout the day.
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Store at controlled room temperature (59° to 86°F). Protect from moisture.
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